- Bcr 2000 only working in preset 1 pro#
- Bcr 2000 only working in preset 1 trial#
- Bcr 2000 only working in preset 1 plus#
16 The best approach for achieving consistent and comparable quantitative data on a global scale would be to use internationally established reference reagents. The existing RQ-PCR methods in use around the world use different techniques and various control genes, leading to marked variation in reported BCR-ABL values. An association was demonstrated between the log reduction scale for determining MMR and a quantitative value using different methods and control genes. A BCR-ABL/ ABL% value in the German laboratory equivalent to the MMR value in the Australian laboratory was calculated by an exchange of patient samples. One process to align data has been undertaken between the IRIS participating laboratory of Hughes and Branford in Australia and the laboratory of Hochhaus and Müller in Germany. Serial molecular analysis within a laboratory will certainly provide benefit for individual patients, but alignment of BCR-ABL values is necessary for several reasons: the use of common clinical decision values, facilitation of patient mobility between clinics that use different testing laboratories, and consistent interpretation of clinical research data, including those to be considered by regulatory authorities. Clearly, a process for accurate alignment of BCR-ABL values in each laboratory to the original MMR value will aid in the consistent measurement of MMR throughout the world. 8 Establishment of a value for MMR in other laboratories equivalent to that established in the IRIS study has not been straightforward. 8, 9 For this trial, 3 testing laboratories standardized their RQ-PCR methods using a standardized baseline, and MMR was a 3-log reduction from this level.
Bcr 2000 only working in preset 1 trial#
The trial that established MMR as a clinically relevant end point was the IRIS study. This indicates that the IS can deliver accurate comparison of molecular response rates between clinical trials when measured by different laboratories.
Bcr 2000 only working in preset 1 plus#
However, irrespective of precision, when the bias was plus or minus 1.2-fold as achieved by 89% of methods, there was good agreement between the overall MMR rates. When not met, the MMR concordance was 74% or less. These criteria were met by 58% of methods. When methods achieved an average BCR-ABL difference of plus or minus 1.2-fold from the reference method and 95% limits of agreement within plus or minus 5-fold, the MMR concordance was 91%. We determined performance characteristics (bias and precision) for consistent interpretation of MMR after IS conversion. A validation procedure was completed for 19 methods. Alignment was achieved by application of laboratory-specific conversion factors calculated by comparisons performed with patient samples against a reference method. We aligned BCR-ABL values generated by 38 laboratories to an international scale (IS) where a major molecular response (MMR) is 0.1% or less. This will aid clinical decisions for individual patients with chronic myeloid leukemia (CML) and assist interpretation of results from clinical studies. So I tried the google translator.An international basis for comparison of BCR-ABL mRNA levels is required for the common interpretation of data derived from individual laboratories. My English is unfortunately more than bad. The tracks could be found on the Search button to the left or right deck loaded. Perhaps it is on Wheels as well as the Search function. Some of the other settings work, some not. Press Buttom scratch on! Now we have a midi signal with which we track forward and backward movement.
Bcr 2000 only working in preset 1 pro#
It also works with tractor Pro! I've tested it.ģrd Traktor Pro activate MIDI Yoke NT: 1 as inputĤth Traktor Pro De-activate BCD-2000 inputĥth Traktor Pro Activate BCD-2000 output. The solution is: Behringer BCD-2000 Jogwheel Fix for Native Instruments Traktor 3. Now the bad: There are many new settings for the other functions. The old problem with the Jogs in the BCD2000 is, that they only run in one direction.įirst the good news: There is a solution! Especially the effect of switching on the tempo/bend slider is well managed.
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